Lora K Heisler Selected Research

Appetite Depressants (Anorectics)

12/2016	Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite.
10/2014	5-HT obesity medication efficacy via POMC activation is maintained during aging.
6/2014	Distribution of cells responsive to 5-HT₆ receptor antagonist-induced hypophagia.
6/2013	5-HT2C receptor agonist anorectic efficacy potentiated by 5-HT1B receptor agonist coapplication: an effect mediated via increased proportion of pro-opiomelanocortin neurons activated.
9/2011	Glucokinase inhibitor glucosamine stimulates feeding and activates hypothalamic neuropeptide Y and orexin neurons.
11/2007	Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways.
6/2003	Central serotonin and melanocortin pathways regulating energy homeostasis.

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Lora K Heisler Research Topics

Disease

25	Obesity 01/2021 - 07/2002
17	Body Weight (Weight, Body) 01/2021 - 10/2005
11	AIDS-Related Complex (ARC) 01/2020 - 06/2003
8	Hypoglycemia (Reactive Hypoglycemia) 11/2018 - 04/2010
6	Type 2 Diabetes Mellitus (MODY) 11/2018 - 02/2007
5	Insulin Resistance 01/2021 - 02/2007
4	Hyperphagia (Overeating) 12/2016 - 11/2008
3	Weight Loss (Weight Reduction) 01/2021 - 11/2010
2	Anorexia 11/2010 - 07/2002
1	Inflammation (Inflammations) 01/2018
1	Bulimia (Binge Eating) 01/2017
1	Prader-Willi Syndrome (Syndrome, Prader-Willi) 12/2016
1	Morbid Obesity 03/2016
1	Autism Spectrum Disorder 07/2015
1	Dyslipidemias (Dyslipidemia) 07/2015
1	Psychotic Disorders (Schizoaffective Disorder) 07/2015
1	Starvation 12/2014
1	Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy) 01/2012
1	Weight Gain 11/2010
1	Hyperinsulinism (Hyperinsulinemia) 12/2008

Drug/Important Bio-Agent (IBA)

16	Serotonin (5 Hydroxytryptamine)IBA 01/2021 - 06/2003
14	Glucose (Dextrose)FDA LinkGeneric 11/2018 - 02/2007
11	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2020 - 06/2003
7	Appetite Depressants (Anorectics)IBA 12/2016 - 06/2003
6	Insulin (Novolin)FDA Link 01/2021 - 11/2007
5	lorcaserinIBA 01/2021 - 10/2014
5	5-HT2C Serotonin ReceptorIBA 01/2021 - 11/2007
5	LeptinIBA 01/2020 - 10/2012
5	MelanocortinsIBA 11/2010 - 07/2002
4	FenfluramineIBA 01/2021 - 11/2010
4	Hormones (Hormone)IBA 01/2020 - 04/2011
4	Glucagon (Glukagon)FDA Link 11/2018 - 04/2012
4	Epinephrine (Adrenaline)FDA LinkGeneric 11/2018 - 04/2011
4	Peptides (Polypeptides)IBA 04/2016 - 01/2007
4	Melanocortin Receptors (Melanocortin Receptor)IBA 09/2011 - 07/2006
3	Leptin ReceptorsIBA 01/2018 - 10/2012
3	Messenger RNA (mRNA)IBA 12/2016 - 03/2008
3	Cholecystokinin (Pancreozymin)IBA 01/2016 - 12/2014
2	sibutramine (Meridia)FDA Link 01/2021 - 10/2014
2	Blood Glucose (Blood Sugar)IBA 01/2021 - 11/2018
2	Hypoglycemic Agents (Hypoglycemics)IBA 11/2018 - 12/2016
2	GlucokinaseIBA 11/2018 - 04/2010
2	LipidsIBA 07/2015 - 12/2008
2	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 11/2010 - 11/2007
1	Phentermine (Adipex-P)FDA LinkGeneric 01/2021
1	5-carboxamidotryptamineIBA 01/2020
1	Serotonin ReceptorsIBA 01/2020
1	NestinIBA 11/2018
1	Streptozocin (Streptozotocin)FDA Link 11/2018
1	Amyloid beta-PeptidesIBA 01/2018
1	Peptide Hydrolases (Proteases)FDA Link 01/2018
1	Small Nucleolar RNA (snoRNA)IBA 12/2016
1	RNA Precursors (Precursor, mRNA)IBA 12/2016
1	RNA (Ribonucleic Acid)IBA 12/2016
1	CatalaseIBA 12/2016
1	AMP-Activated Protein KinasesIBA 05/2016
1	GhrelinIBA 05/2016
1	Risperidone (Risperdal Consta)FDA LinkGeneric 07/2015
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 07/2015
1	Antipsychotic Agents (Antipsychotics)IBA 07/2015
1	pyrrolidonyl-beta-naphthylamideIBA 12/2014
1	NeuropeptidesIBA 12/2014
1	GlucocorticoidsIBA 12/2014
1	Pharmaceutical PreparationsIBA 06/2013
1	CalciumIBA 06/2013
1	Biological ProductsIBA 10/2012
1	CorticosteroneIBA 04/2012
1	Proteins (Proteins, Gene)FDA Link 01/2012
1	Green Fluorescent ProteinsIBA 11/2011
1	Melanocyte-Stimulating Hormones (MSH)IBA 09/2011
1	Neuropeptide YIBA 09/2011
1	alpha-MSHIBA 09/2011
1	Neurotransmitter Agents (Neurotransmitter)IBA 06/2011
1	5-HT1B Serotonin ReceptorIBA 11/2010
1	HexokinaseIBA 04/2010
1	Glucosamine (Dona)IBA 04/2010
1	A-factor (Streptomyces)IBA 12/2008
1	Peptide Receptors (Peptide Receptor)IBA 07/2008
1	NociceptinIBA 07/2008

Therapy/Procedure

2	Therapeutics 01/2017 - 07/2008
1	Lasers (Laser) 01/2020
1	Glycemic Control 10/2017
1	Protein-Restricted Diet (Diet, Protein Restricted) 04/2016
1	Drug Therapy (Chemotherapy) 10/2014
1	Injections 04/2011